The Atopic March. A Literature Review

  • Juan F. Salazar-Espinosa. University of Caldas, Manizales, Colombia
Keywords: Atopic dermatitis, asthma, allergy, atopy, Th2 response, atopic march

Abstract

The atopic march is defined as the progression of atopic diseases, generally during childhood, such as atopic dermatitis, asthma, allergic rhinitis and food allergies. The main risk factors for developing these atopic diseases include genetics, aeroallergens, food allergens, latefood introduction to the infant, and living in developing countries. The immunologic contributors to this problem include the Th2 response, epigenetics, and lack of certain factors like thymic stromal lymphopoietin (TSLP) and filaggrin. As a whole, the therapeutic approach has been changing during recent years because of the discovery of new factors involved in this problem. This article explains the definition of atopic march, the immunological pathway, clinical features, epidemiology and therapeutic approaches to create a context for the broader understanding of this important condition.

Author Biography

Juan F. Salazar-Espinosa., University of Caldas, Manizales, Colombia

Juan F. Salazar-Espinosa is cu¬rrently a 3rd year medical student of University of Caldas, Manizales, Colom¬bia of a six year program. He is also the treasurer of the Medical Student’s Scientific Association of Universidad de Caldas (ACEMCAL).

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Published
2014-08-22
How to Cite
Salazar-Espinosa., J. F. (2014). The Atopic March. A Literature Review. International Journal of Medical Students, 2(3), 119-124. https://doi.org/10.5195/ijms.2014.100
Section
Review