Diagnostic Value of Pleural Fluid N-Terminal pro-Brain Natriuretic Peptide Levels in Patients with Cardiovascular Diseases

Authors

Keywords:

Pleural effusion, Cardiac disease

Abstract

Background: Pleural effusion is a prevelant complication of multiple pathologies leading to annual incidence of 3000 cases per million. The delay in diagnosing the cause of pleural effusion and treatment of the underlying cause is the major factor of mortality.

 

Objectives: The study aims to establish the accuracy of pleural pro-Bnp in evaluating the cardiac causes of pleural effusion.

 

Methods: The study  evaluates the level of pro-BNP measured in cardiac and non cardiac causes to identify its role in diagnosing the cause of effusion.

 

Results: Pro-BNP levels are significantly lower in patients with pleural effusion due to hepatic hydrothorax  which is 84% lower than the referral level of cardiac causes with a base value of >1714pg/ml, 94 % less in patients with tuberculosis related pleural effusion and 91% less in parapneumonic and 78% lower in effusion due to malignant causes of pleural effusion. hence showing the tests accuracy in distinguishing cardiac from non cardiac causes of pleural effusion. 

 

Conclusion: Pro BNP levels can aid in distinguishing cardiac from non cardiac causes of pleural effusion. Early detection of cause with accuracy can help in early treatment and low mortality.

 

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Published

2026-08-19

How to Cite

Gurram, Y. S., Shah, P., Ammineni, D. K., & Dr. Srijamya. (2026). Diagnostic Value of Pleural Fluid N-Terminal pro-Brain Natriuretic Peptide Levels in Patients with Cardiovascular Diseases. International Journal of Medical Students. Retrieved from https://ijms.info/IJMS/article/view/4863

Issue

Forthcoming

Section

Abstracts of the WCMSR

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Copyright (c) 2026 Yamini Saraswathi Gurram, Parth Shah, Dr. Kavya Ammineni, Dr. Srijamya

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