A Review of Palliative Care Service Delivery Models and Patient Outcomes for Adults with Cancer in Selected East and Southeast Asian Countries
DOI:
https://doi.org/10.5195/ijms.2023.1919Keywords:
Palliative care (PC), World Health Organization (WHO), Lancet Commission on Global Access to Palliative Care and Pain Relief, International Association for Hospice and Palliative Care (IAHPC), Enhanced Supportive Care (ESC) guidelines, European Society for Medical Oncology (ESMO), Positive outcomes of palliative care, Early palliative care, Meta-analyses on the effects of early palliative care, Models of PC delivery, Inpatient hospital-based PC models, Outpatient PC models, Home-based PC models, Hybrid standardized PC model, Discussion on PC delivery models, Trends in PC service delivery, Multidisciplinary intervention in PC, Early PC provision, Policy recommendations for PC, Specialized PC services for hematological malignancies, Hybrid PC model effectiveness, Evaluation of national standardized PC modelsAbstract
Cancer is one of the key leading causes of deaths worldwide, with a disproportionately high burden in Asia in terms of incidence and mortality. Guidelines and recommendations published by the World Health Organization (WHO) state palliative care as an essential service for patients with cancer and other chronic diseases. Currently, there is extensive evidence regarding different models of palliative care delivery. However, development of palliative care services remains fragmented in Asia, and more research is needed to synthesize available models of care in this region and provide the latest evidence-based information for healthcare providers. This narrative review identified 11 peer-reviewed studies published after 2017 that reported both on models of palliative care service delivery and outcomes for adult patients with cancer in selected East and Southeast Asian countries. This review is beneficial by providing a detailed summary of the models of care adopted by these countries, and their impact on patient outcomes. It is hoped that the evidence will also generate momentum for continued conversation around palliative care development in Asia.
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References
World Health Organization. Palliative care. Available from: https://www.who.int/europe/news-room/fact-sheets/item/palliative-care. Last updated May 16, 2010; cited Jul 18, 2022.
Radbruch L, De Lima L, Knaul F, Wenk R, Ali Z, Bhatnaghar S, et al. Redefining palliative care—a new consensus-based definition. J Pain Symptom Manage. 2020;60(4):754–64. DOI: https://doi.org/10.1016/j.jpainsymman.2020.04.027
Berman R, Elliott E, LaMola L, Mula C, Talbot H, Kong S, et al. O-1 Enhanced supportive care in cancer. BMJ Support Palliat Care. 2017;7Suppl 1:A1-A54. DOI: https://doi.org/10.1136/bmjspcare-2017-00133.1
Jordan K, Aapro M, Kaasa S, Ripamonti CI, Scotté F, Strasser F, et al. European Society for Medical Oncology (ESMO) position paper on supportive and palliative care. Ann Oncol. 2018;29(1):36–43. DOI: https://doi.org/10.1093/annonc/mdx757
Gaertner J, Siemens W, Meerpohl JJ, Antes G, Meffert C, Xander C, et al. Effect of specialist palliative care services on quality of life in adults with advanced incurable illness in hospital, hospice, or community settings: Systematic review and meta-analysis. BMJ. 2017;357:j2925. DOI: https://doi.org/10.1136/bmj.j2925
Huo B, Song Y, Chang L, Tan B. Effects of early palliative care on patients with incurable cancer: A meta‐analysis and systematic review. Eur J Cancer Care (Engl). 2022;31(6):e13620. DOI: https://doi.org/10.1111/ecc.13620
Mathews J, Hannon B, Zimmermann C. Models of integration of specialized palliative care with oncology. Curr Treat Options Oncol. 2021;22(5):44. DOI: https://doi.org/10.1007/s11864-021-00836-1
Cassel JB, Albrecht TA. Emerging models of providing oncology palliative care. Semin Oncol Nurs. 2018;34(3):202-14. DOI: https://doi.org/10.1016/j.soncn.2018.06.002
Hui D, Bruera E. Models of integration of oncology and palliative care. Ann Palliat Med. 2015;4(3):89-98. DOI: https://doi.org/10.1093/med/9780199329755.003.0001
Luckett T, Phillips J, Agar M, Virdun C, Green A, Davidson PM. Elements of effective palliative care models: A rapid review. BMC Health Serv Res. 2014; 14:136. DOI: https://doi.org/10.1186/1472-6963-14-136
World Health Organization. Framework on integrated, people centered health services. Available from: https://apps.who.int/gb/ebwha/pdf_files/wha69/a69_39-en.pdf. Last updated Apr 16, 2016; cited Jul 15, 2022.
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-249. DOI: https://doi.org/10.3322/caac.21660
Zou H, Li Z, Tian X, Ren Y. The top 5 causes of death in China from 2000 to 2017. Sci Rep. 2022;12(1):8119. DOI: https://doi.org/10.1038/s41598-022-12256-8
Clark D, Baur N, Clelland D, Garralda E, López-Fidalgo J, Connor S, et al. Mapping levels of palliative care development in 198 countries: The situation in 2017. J Pain Symptom Manage. 2020;59(4):794-807. DOI: https://doi.org/10.1016/j.jpainsymman.2019.11.009
Evans CJ, Ison L, Ellis-Smith C, Nicholson C, Costa A, Oluyase AO, et al. Rapid Scoping Review of Service Delivery Models to Maximise Quality of Life for Older People at the End of Life. Milbank Q. 2019;97(1):113-75. DOI: https://doi.org/10.1111/1468-0009.12373
Singh T, Harding R. Palliative care in South Asia: A systematic review of the evidence for care models, interventions, and outcomes. BMC Res Notes. 2015;8:172. DOI: https://doi.org/10.1186/s13104-015-1102-3
Lu Y, Gu Y, Yu W. Hospice and palliative care in China: Development and challenges. Asia Pac J Oncol Nurs. 2018;5(1):26-32. DOI: https://doi.org/10.4103/apjon.apjon_72_17
Chan YC, Yang ML, Ho HF. Characteristics and outcomes of patients referred to an emergency department-based end-of-life care service in Hong Kong: A retrospective cohort study. Am J Hosp Palliat Care. 2021;38(1):25-31. DOI: https://doi.org/10.1177/1049909120926148
World Health Organization. Integrating palliative care and symptom relief into primary health care. Available from: https://apps.who.int/iris/bitstream/handle/10665/274559/9789241514477-eng.pdf?ua=1. Last updated Oct 16, 2018; cited Jul 26, 2022.
Yamaguchi T, Kuriya M, Morita T, Agar M, Choi YS, Goh C, et al. Palliative Care Development in the Asia-Pacific Region: An international survey from the Asia Pacific Hospice Palliative Care Network (APHN). BMJ Support Palliat Care. 2017;7(1):23-31. DOI: https://doi.org/10.1136/bmjspcare-2013-000588
Lin Goh SS. Singapore takes six steps forward in ‘The Quality of Death Index' rankings. Asia Pac J Oncol Nurs. 2018;5(1):21-5. DOI: https://doi.org/10.4103/apjon.apjon_66_17
Chua GP, Pang GS, Yee AC, Neo PS, Zhou S, Lim C, et al. Supporting the patients with advanced cancer and their family caregivers: What are their palliative care needs?. BMC Cancer. 2020;20(1):768. DOI: https://doi.org/10.1186/s12885-020-07239-9
Hasegawa T, Yamagishi A, Sugishita A, Akechi T, Kubota Y, Shimoyama S. Integrating home palliative care in oncology: A qualitative study to identify barriers and facilitators. Support Care Cancer. 2022;30(6):5211-19. DOI: https://doi.org/10.1007/s00520-022-06950-6
Nakazawa Y, Kato M, Miyashita M, Morita T, Ogawa A, Kizawa Y. Growth and challenges in hospital palliative cancer care services: An analysis of nationwide surveys over a decade in Japan. J Pain Symptom Manage. 2021;61(6):1155-64. DOI: https://doi.org/10.1016/j.jpainsymman.2020.10.023
Fukui S, Yoshiuchi K, Fujita J, Sawai M, Watanabe M. Japanese people’s preference for place of end-of-life care and death: A population-based nationwide survey. J Pain Symptom Manage. 2011;42(6):882-92. DOI: https://doi.org/10.1016/j.jpainsymman.2011.02.024
Rhee YJ. Hospice and palliative care services in South Korea supported by the National Health Insurance (NHI) program. Health. 2015;07(06):689–95. DOI: https://doi.org/10.4236/health.2015.76082
Mai TT, Lee E, Cho H, Chang YJ. Increasing trend in hospital deaths consistent among older decedents in Korea: A population-based study using Death registration database, 2001–2014. BMC Palliat Care. 2018;17(1):16. DOI: https://doi.org/10.1186/s12904-017-0269-x
Cheng S-Y, Chen C-Y, Chiu T-Y. Advances of hospice palliative care in Taiwan. Korean J Hosp Palliat Care. 2016;19(4):292–5. DOI: https://doi.org/10.14475/kjhpc.2016.19.4.292
Chiang S-W, Wu S-C, Peng T-C. The experience to implement palliative care in long-term care facilities: A grounded theory study of caregivers. Asian Nurs Res. 2021;15(1):15-22. DOI: https://doi.org/10.1016/j.anr.2020.10.006
Chaiviboontham S, Pokpalagon P. Palliative care model in Thailand. Int J Palliat Nurs. 2021;27(3):132-46. DOI: https://doi.org/10.12968/ijpn.2021.27.3.132
Wu H, Lin P, Yang S, Zhang W, Tao W. Cost-utility analysis of palliative care in patients with advanced cancer: A retrospective study. BMC Palliat Care. 2021;20(1):126. DOI: https://doi.org/10.1186/s12904-021-00816-0
Yang GM, Zhou S, Xu Z, Goh SSL, Zhu X, Chong DQQ, et al. Comparing the effect of a consult model versus an integrated palliative care and medical oncology co-rounding model on Health Care Utilization in an acute hospital – an open-label stepped-wedge cluster-randomized trial. Palliat Med. 2021;35(8):1578-89. DOI: https://doi.org/10.1177/02692163211022957
Meijuan Yang G, Kanesvaran R, Hui-Shan Neo S, Chung Pheng Yee A, Block SD, Bun Cheung Y. Pilot study of a palliative care and medical oncology co-rounding model for advanced cancer inpatients in a tertiary hospital in Singapore. J Palliat Med. 2018;21(1):95-8. DOI: https://doi.org/10.1089/jpm.2017.0186
Chang L-F, Wu L-F, Lin C-K, Ho C-L, Hung Y-C, Pan H-H. Inpatient hospice palliative care unit and palliative consultation service enhance comprehensive quality of life outcomes in terminally ill cancer patients: A prospective longitudinal study. Int J Environ Res Public Health. 2021;18(17):8992. DOI: https://doi.org/10.3390/ijerph18178992
Chan KY, Gill H, Chan TS, Li CW, Tsang KW, Au HY, et al. Early integrated palliative care for Haematology Cancer Patients-The impact on symptom burden in Hong Kong. Ann Palliat Med. 2021;10(6):6316-24. DOI: https://doi.org/10.21037/apm-21-276
Chan HY-lai, Chung CK-man, Tam SS-chai, Chow RS-kuen. Community palliative care services on addressing physical and psychosocial needs in people with advanced illness: A prospective cohort study. BMC Palliat Care. 2021;20(1):143. DOI: https://doi.org/10.1186/s12904-021-00840-0
Lam T-C, Chan S-K, Choi C-W, Tsang K-C, Yuen K-K, Soong I, et al. Integrative Palliative Care Service Model improved end-of-life care and overall survival of advanced cancer patients in Hong Kong: A review of ten-year territory-wide cohort. J Palliat Med. 2021;24(9):1314-20. DOI: https://doi.org/10.1089/jpm.2020.0640
Hsu H-S, Wu T-H, Lin C-Y, Lin C-C, Chen T-P, Lin W-Y. Enhanced home palliative care could reduce emergency department visits due to non-organic dyspnea among cancer patients: A retrospective cohort study. BMC Palliat Care. 2021;20(1):42. DOI: https://doi.org/10.1186/s12904-021-00713-6
Yang B, Cui Z, Zhu X, Deng M, Pan Y, Li R, et al. Clinical pain management by a multidisciplinary palliative care team. Medicine (Baltimore). 2020;99(48):e23312. DOI: https://doi.org/10.1097/MD.0000000000023312
Choi S-O, Kim S-N, Shin S-H, Ryu J-S, Baik J-W, Kim J-R, et al. Evaluation of outcomes of the Busan Community-based Palliative Care Project in Korea. Asian Nurs. 2018;12(4):286-92. DOI: https://doi.org/10.1016/j.anr.2018.11.001
Kim S-N, Choi S-O, Shin SH, Ryu J-S, Baik J-W. Development of a community-based palliative care model for advance cancer patients in public health centers in Busan, Korea. Cancer Res Treat. 2017;49(3):559-68. DOI: https://doi.org/10.4143/crt.2016.276
Duke-NUS Medical School. End of Life Utilization and Costs and the Role of Palliative Care in Treating Patients with Advanced Cancer. Available from: https://www.duke-nus.edu.sg/lcpc/resources/policy-briefs/lcpc-policy-brief-2. Last updated Nov 29, 2021; cited Jul 31, 2022.
Janssen Oncology. Make Blood Cancer Visible – Asia Pacific Report. Available from: https://www.janssen.com/sites/www_janssen_com_apac/files/mbcv_report_en_digital_final-min.pdf#view=FitH,100. Last updated Sep 14, 2018; cited Jul 31, 2022.
Meriggi F. Dyspnea in cancer patients: A well-known and neglected symptom. Rev Recent Clin Trials. 2018;13(2):84-8. DOI: https://doi.org/10.2174/1574887113666180326112116
Tam KI, Che SL, Zhu M, Leong SM. Knowledge of palliative care and preference of end of life care: A cross-sectional survey of residents in the Chinese socio-cultural background of Macao. BMC Palliat Care. 2021;20(1):87. DOI: https://doi.org/10.1186/s12904-021-00798-z
Hoare S, Antunes B, Kelly MP, Barclay S. End-of-life care quality measures: Beyond Place of Death. BMJ Supportive & Palliative Care. 2022; spcare-2022-003841. DOI: https://doi.org/10.1136/spcare-2022-003841
Chung H, Harding R, Guo P. Palliative care in the Greater China region: A systematic review of needs, models, and outcomes. J Pain Symptom Manage. 2021;61(3):585-612. DOI: https://doi.org/10.1016/j.jpainsymman.2020.08.040
Zhao X-X, Cui M, Geng Y-H, Yang Y-L. A systematic review and meta-analysis of randomized controlled trials of palliative care for pain among Chinese adults with cancer. BMC Palliat Care. 2019;18(1):69. DOI: https://doi.org/10.1186/s12904-019-0456-z
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