Predictors of Cerebral Arteriovenous Malformation Mortality: A Single-center, Five-year Retrospective Study


  • Patricio Garcia-Espinosa Medical student. Universidad Autónoma de Nuevo León, Mexico
  • Edgar Botello-Hernández Universidad Autónoma de Nuevo León
  • Gabriela Torres-Hernández Universidad Autónoma de Nuevo León
  • Clarissa Guerrero-Cavazos Universidad Autónoma de Nuevo León, Mexico
  • Estefania Villareal-Garza Universidad Autónoma de Nuevo León, Mexico
  • Andrea Flores-Rodriguez Universidad Autónoma de Nuevo León



Nervous System Malformation, Arteriovenous Fistula, Cerebral Hemorrhage, Intracranial Hemorrhages, Arteriovenous Malformation


Background: Arteriovenous Malformations (AVMs) are abnormalities in intracranial vessels between the arterial and venous systems. This study aimed to identify the predictors of mortality in patients that presented to our hospital with AVMs, ruptured or unruptured, and correlate them to those available in the literature.

Methods: An analytical, observational, retrospective study was performed to review data of patients with cerebral AVMs in the University Hospital “Dr José Eleuterio González” from January 2016 to December 2020. Clinical files were reviewed based on AVMs diagnosis according to the  International Classification of Diseases 10th Revision, ICD-10. Variables were subjected to a univariate analysis and those found significant (p-value < 0.05) were subjected to a logistic regression.

Results: A total of 80 patients were included in our study. Most of the participants were females (56.3%) and three were pregnant. The most common presenting symptom was holocranial headache (34 cases) occurring between the hours of 22:00 to 7:00. The most significant predictors of mortality were a total bleeding volume greater than 9.18 cm3 (p = 0.010), the presence of more than one symptom (p = 0.041), and a history of previous cerebral intraparenchymal hemorrhage (p = 0.014).

Conclusion: Results demonstrated an important association between intracranial bleeding and mortality. Ultimately, more prospective studies are needed to determine predictor factors for mortality in AVMs patients.


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How to Cite

Garcia-Espinosa, P., Botello-Hernández, E. ., Torres-Hernández, G. ., Guerrero-Cavazos, C. ., Villareal-Garza, E., & Flores-Rodriguez , A. . (2021). Predictors of Cerebral Arteriovenous Malformation Mortality: A Single-center, Five-year Retrospective Study. International Journal of Medical Students, 9(3), 213–218.



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